Treatment For this Muscle Condition

Myasthenia gravis is a neuromuscular condition that results in fatigue and weakness of the voluntary muscles. The problem is a breakdown in communication between nerves and muscles. Normally, a chemical called acetylcholine sends nerve impulses to the muscles. In myasthenia gravis, the immune system produces antibodies which destroy or block receptor sites for acetylcholine in the muscles themselves. Muscles of the face and neck are most affected; however any muscle may be involved with this condition. Double vision, drooping eyelids, and difficulty chewing, swallowing, or breathing are all possible symptoms. Weakness of the limbs may also occur. While there is no cure for this condition, treatments are available to help alleviate the associated symptoms.

Cholinesterase inhibitors such as pyridostigmine (Mestinon) and neostigmine (Prostigmin) often improve neuromuscular communication, resulting in better muscle contraction and strength. Steroids decrease antibody production, however prolonged use may lead to serious side effects. Other medications which alter immune system function and may be prescribed for this condition include azathioprine (Imuran), mycophenolate mofetil (CellCept), cyclophosphamide (Cytoxan) or cyclosporine (Sandimmune, Neoral).