Medicines Prescribed for Psoriasis

Psoriasis is a chronic skin condition in which there is rapid turnover of cells. Health researchers have determined that inappropriate functioning of the immune system leads to this condition. A type of white blood cell known as the T cell becomes overactive, leading to rapid cell turnover. A build-up of skin cells results in thick silvery scales. The scales may cover red patches of skin. Other symptoms of psoriasis may include dry skin, thickened nails, and stiff joints. The severity of this condition may range from only a small affected area to a large area of scaling. Factors that may trigger T cell malfunction include infections, injury, stress, and certain drugs, such as lithium and certain medications for high blood pressure.

Topical steroids are prescribed for the treatment of mild to moderate psoriasis. They work by slowing cell turnover, thereby reducing inflammation. Calcipotriene (Dovonex) is a vitamin D analogue prescribed as a cream, ointment, or solution for the treatment of psoriasis. For treatment of severe psoriasis, oral or injected medications may be prescribed. Methotrexate, azathioprine, and cyclosporine are oral drugs that may be prescribed to reduce inflammation. Immune modulator drugs, such as etanercept (Enbrel) and infliximab (Remicade) are sometimes given.