Parkinson’s Disease Involves Body Muscles

Parkinson’s disease is a progressive condition affecting a person’s control of how their muscles move. Nerve cells that normally release the chemical dopamine are damaged or destroyed in persons affected by this condition. Dopamine helps in the transmission of signals from the brain to the muscles. Although the cause of this condition is unknown, it is thought that genetic and environmental factors play a role. In addition, certain drugs and conditions may cause Parkinson’s-like symptoms. Haloperidol (Haldol) and chlorpromazine (Thorazine) are sometimes prescribed for mental conditions that may lead to symptoms similar to those of Parkinson’s. Symptoms of Parkinson’s include trembling, slowed motion, muscle rigidity, and impaired speech.

Although there is no current cure available for Parkinson’s disease, drugs are available to treat this condition. Carbidopa-levodpoa (Sinemet) is often prescribed. Other drugs prescribed include the dopamine agonists such as ropinirole (Requip) and pramipexole (Mirapex). Selegiline (Eldepryl) inhibits an enzyme that metabolizes dopamine in the brain, thereby preventing the breakdown of dopamine. This medication is sometimes prescribed in combination with Sinemet.