Sunday, March 9, 2008

Different Types of Drugs for Gout

Gout is characterized by sudden painful attacks in the joints, often occurring at night. This condition is a form of arthritis that is more likely to affect men than women. However the likelihood for women to be affected increases after menopause. Uric acid is a substance that is normally produced by the body, however may build up if over-produced, or if the kidneys do not excrete enough. High levels of uric acid in the blood lead to the formation of urate crystals. Accumulation of such crystals around the joint causes inflammation and intense pain, characterizing an attack of gout. The large joint of the big toe is usually affected. Other joints in the feet, ankles, knees, hands, and wrists also may become swollen and tender.

Medications available for the treatment of gout include nonsteroidal anti-inflammatory drugs (NSAIDs), colchicine, and steroids. NSAIDs are used to alleviate inflammation and pain associated with this condition. Ibuprofen (Advil, Motrin) and naproxen (Aleve) are examples of NSAIDs available in both over-the-counter and prescription strength. Colchicine may be prescribed for persons who are unable to take NSAIDs. Steroids, such as prednisone, also may alleviate inflammation and pain, and may be prescribed for persons who are unable to tolerate NSAIDs or colchicine

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