Sunday, April 27, 2008

Sjogren’s Syndrome: Control of Symptoms

     Sjogren’s syndrome is a condition of an abnormally functioning immune system. Mucous membranes of the eyes and mouth are commonly affected, although other tissues may be involved. This condition often occurs in persons affected by other conditions of the immune system, such as lupus and rheumatoid arthritis. The cause of Sjogren’s syndrome is unknown; however certain factors such as infections, heredity, and certain hormones are thought to potentially play a role in the development of this condition. Common signs and symptoms include dry eyes, dry mouth, fatigue, and dry skin.  Joint pain and swelling also may occur.

     Although there is no cure available for Sjogren’s syndrome, treatments are available to provide relief for symptoms. Nonsteroidal anti-inflammatory drugs, such as ibuprofen (Advil), work to alleviate pain and inflammation. Steroids help reduce inflammation, however serious side effects may result from long term use. Hydroxychloroquine (Plaquenil) is an antimalarial medication that works to decrease joint inflammation. Pilocarpine (Salagen) may be prescribed to alleviate dry mouth. Cevimeline (Evoxac) also works to relieve dry mouth. Cyclosporine (Restasis) eye-drops may be prescribed for persons affected by Sjögren's syndrome.

Henrik Samuel Conrad Sjögren (July 23, 1899 - September 17, 1986)

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