Unstable angina is classified as an acute coronary syndrome (ACS), which means the condition is a result of a sudden decrease in blood flowing to the heart. When this happens, immediate medical attention is required. The condition is caused by an imbalance in supply and demand of oxygen for the heart. This imbalance can originate from the buildup of fatty deposits (known as plaques) in the arteries, which leads to narrowing of the arteries. Unstable angina often causes chest pain at rest, severe chest pain, or intense, frequent, or prolonged chest pain episodes.
Persons who experience unstable angina should receive nitroglycerin sublingually (under the tongue) at first. Antithrombotic therapies, such as aspirin and clopidogrel (Plavix), may be given as soon as possible to prevent further blood clotting. In addition, anticoagulant medication, such as enoxaparin (Lovenox) or fondaparinux (Arixtra), which work to further prevent blood clotting, may be administered. For prevention of an ACS such as unstable angina, diets low in saturated-fat, trans-fat, salt, and cholesterol and high in fruits, vegetables, and whole grains are also encouraged. Regular aerobic exercise is also recommended. Persons with high cholesterol may be prescribed a statin medication, such as simvastatin (Zocor).
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