Peritonitis, or inflammation of the peritoneum, is caused by a bacterial infection. The peritoneum lines the stomach. Escherichia coli and Klebsiella are bacteria that are commonly found in the stomach, and are commonly the bacteria that cause this condition. However, other types of bacteria, such as streptococcal and staphylococcal bacteria, may also lead to peritonitis. Signs and symptoms include fever, abdominal pain, changes in mental status, and diarrhea. Peritonitis can be caused by peritoneal dialysis or a buildup of fluid in the abdomen. Peritoneal dialysis is a procedure to remove waste from the body when the kidneys are not functioning properly, and can lead to peritonitis due to contamination associated with the procedure. Buildup of fluid in the abdomen, also known as ascites, can result from damage to the liver, and can lead to infection.
Cefotaxime (Claforan) is a cephalosporin antibiotic that may be prescribed for peritonitis. Metronidazole (Flagyl) is an antibacterial that may be prescribed in addition to cefotaxime for secondary bacterial peritonitis. Ofloxacin (Floxin) may be taken by mouth for this condition. Peritonitis can be prevented with good hygiene during peritoneal dialysis. If peritoneal dialysis is the cause of the peritonitis, a different form of dialysis may be used.
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