Treatment for Lennox-Gastaut Syndrome

Lennox-Gastaut Syndrome is a neurological condition in which severe seizures occur during childhood, usually in children 7 years of age or younger. Children with this condition may experience different types of seizures. They may be characterized by staring, muscle spasms, loss of consciousness and falling, or pupil dilation. The frequency of seizures also varies; persons may experience times of frequent seizure activity, and then other times of reduced seizure activity. Impaired metal functioning also may be present. The condition could be caused be genetics, meningitis, or a head injury; however the exact cause may not be known.

Although there is currently no cure for this condition, there are many medications available that may be prescribed for children with Lennox-Gastaut Syndrome. Lamotrigine (Lamictal) is an antiepileptic drug that helps prevent seizures from occurring by preventing the release of an excitatory substance called glutamate. Topiramate (Topamax) is an anticonvulsant medication that decreases electrical activity in the brain to prevent seizures. Valproate (Depakote) and felbamate (Felbatol) are anticonvulsant medications that may be prescribed. The ketogenic diet may be recommended, in addition to prescribed medications.