Treatment of Angioedema & Hives

Angioedema is a swelling just beneath the surface of the skin. In contrast, hives are swellings on the surface of the skin. Swelling may occur near the eyes, lips, throat, hands, and feet. Breathing difficulties can also occur with angioedema. An allergic reaction can lead to either angioedema or hives. When the body detects the allergen, histamine and other substances are released into the blood. Certain types of food, pets, and medications can all lead to angioedema and hives. Allergies to penicillin or sulfa medications can also result in these types of allergic reactions. Angioedema may occur with anaphylaxis, which can be life threatening and necessitates immediate medical attention.

If difficulty breathing occurs, emergency medical attention should be sought immediately. Medications to treat angioedema and hives include antihistamines and corticosteroids. Methylprednisolone (Medrol) and prednisone are steroids that may be taken for about a week. Ranitidine (Zantac) is an antihistamine that works to block histamine and improve symptoms caused by the release of histamine in response to the allergen. Terbutaline is a bronchodilator that can be inhaled to help improve breathing. Epinephrine is usually administered in the case of anaphylaxis.